Cycloserine: amino acid analog antibiotic.
Cycloserine testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Cycloserine: 2D structure drawn from the PubChem record (CID 6234).
68-41-7
C3H6N2O2
102.09 g/mol
Amino acid analog antibiotic
Identity: Cycloserine
IUPAC name: (4R)-4-amino-1,2-oxazolidin-3-one
Method for the $250 identity, purity and quantity test: Chromatographic assay, with detection selected for the compound, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by a nitroprusside color test, condensation products by UV spectrophotometry, specific rotation, pH, loss on drying, residue on ignition, and assay by HPLC with UV at 219 nm. Full testing to the USP Cycloserine monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by a chromatographic assay, with detection selected for the compound. Full testing to the USP Cycloserine monograph is available and quoted.
Cycloserine absorbs moisture and can dimerize or break down, especially in acid. The monograph limits condensation products, and samples should be kept dry and cool.
USP cycloserine is the D enantiomer. A standard HPLC purity test does not separate it from L-cycloserine, so chiral testing is quoted separately.
It is a small, very polar molecule with little UV absorbance, so the lab uses a detection method suited to the compound.
https://pubchem.ncbi.nlm.nih.gov/compound/6234
Identity facts from the USP monograph header for this compound.
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