Deferoxamine mesylate

Deferoxamine mesylate: iron chelating agent (siderophore).

Deferoxamine mesylate testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of Deferoxamine mesylate

Deferoxamine mesylate: 2D structure drawn from the PubChem record (CID 62881).

Compound data

CAS number

138-14-7

Formula

C25H48N6O8 · CH4O3S

Molecular weight

656.79 g/mol

Type

Iron chelating agent (siderophore)

Structure and names

Identity: Deferoxamine mesylate

IUPAC name: N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-N’-(5-aminopentyl)-N’-hydroxybutanediamide;methanesulfonic acid

How Vanguard tests Deferoxamine mesylate

Method for the $250 identity, purity and quantity test: Chromatographic assay, with detection selected for the compound, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC, residue on ignition, chloride and sulfate limit tests, pH, water content, sterility, and bacterial endotoxins. Full testing to the USP Deferoxamine Mesylate monograph is available and quoted.

What's reported

  • Purity, as percent of total peak area
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Deferoxamine Mesylate (CAS 138-14-7; free base CAS 70-51-9)
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Deferoxamine mesylate testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by a chromatographic assay, with detection selected for the compound. Full testing to the USP Deferoxamine Mesylate monograph is available and quoted.

Why is deferoxamine hard to detect by UV?

Deferoxamine has no aromatic ring and absorbs only weakly in the UV, so the lab uses a detection method suited to the compound.

Is the result given as deferoxamine or the mesylate salt?

Raw material is the mesylate salt, and the free base is about 85 percent of the salt weight. The report states which basis the quantity is given on.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/62881

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.