Dimethyl sulfoxide: polar aprotic solvent.
Dimethyl sulfoxide testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Dimethyl sulfoxide: 2D structure drawn from the PubChem record (CID 679).
67-68-5
C2H6OS
78.13 g/mol
Polar aprotic solvent
Identity: Dimethyl sulfoxide
IUPAC name: methylsulfinylmethane
Method for the $250 identity, purity and quantity test: Chromatographic assay, with detection selected for the compound, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and chromatographic retention time, organic impurities by chromatography, nonvolatile residue, an assay calculated from those results, specific gravity, refractive index, acidity by titration, water and UV absorbance. Full testing to the USP Dimethyl Sulfoxide monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by a chromatographic assay, with detection selected for the compound. Full testing to the USP Dimethyl Sulfoxide monograph is available and quoted.
DMSO is a small, volatile liquid with little UV absorbance, so the lab uses a detection method suited to the compound. The USP sets the assay as what remains after impurities and nonvolatile residue are subtracted.
Dimethyl sulfone and dimethyl sulfide are common, along with water, since DMSO takes up moisture from air. The chromatographic test separates the organic impurities, and water is measured separately.
DMSO freezes near room temperature and absorbs water quickly, so samples should be sent in tightly closed glass. Some plastics leach into DMSO and can show up as extra peaks.
https://pubchem.ncbi.nlm.nih.gov/compound/679
Identity facts from the USP monograph header for this compound.
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