Hydrocortisone: corticosteroid (glucocorticoid).
Hydrocortisone testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Hydrocortisone: 2D structure drawn from the PubChem record (CID 5754).
50-23-7
C21H30O5
362.46 g/mol
Corticosteroid (glucocorticoid)
Identity: Hydrocortisone
IUPAC name: (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared and UV spectroscopy, assay by HPLC, organic impurities by HPLC, residue on ignition, optical rotation and loss on drying. Full testing to the USP Hydrocortisone monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC with UV detection for purity and assay, and LC-MS for identity. Full testing to the USP Hydrocortisone monograph is available and quoted.
Yes. Each ester is its own compound with its own mass and retention time. The report names the ester found and gives quantity for that form.
Yes. Creams and ointments are extracted before HPLC. Send the labeled strength and the type of base so the extraction suits the sample.
Yes. Hydrocortisone is the name used for cortisol as a raw material. Cortisone is a different compound with a ketone in place of one hydroxyl group and separates by HPLC.
https://pubchem.ncbi.nlm.nih.gov/compound/5754
Identity facts from the USP monograph header for this compound.
Start an order online, or send the compound name and the tests you need for a quote.
