Lidocaine

Lidocaine: amide local anesthetic.

Purity and quantity by the chromatographic method matched to the compound (HPLC-UV, LC-MS or GC-MS), with identity against a reference standard. $250 per sample; raw powder purity $200. Results in 3 to 5 business days.

Structure

2D structure of Lidocaine

Lidocaine: 2D structure drawn from the PubChem record (CID 3676).

Compound data

CAS number

137-58-6

Formula

C14H22N2O

Molecular weight

234.34 g/mol (monoisotopic 234.17)

Type

amide local anesthetic

Structure and names

IUPAC name: 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide

Other names: lignocaine, xylocaine

How Vanguard tests Lidocaine

Identity, purity and quantity are measured by the chromatographic method matched to the compound (HPLC-UV, LC-MS or GC-MS) against a reference standard, $250 per sample with results in 3 to 5 business days.

Full testing to the USP monographs for Lidocaine and Lidocaine Hydrochloride is available and quoted: identification by infrared absorption (USP <197>), HPLC retention time against the USP reference standard and chemical identification tests, assay by HPLC with UV detection and impurities by HPLC with UV detection.

What's reported

  • Purity, as percent of total peak area
  • Quantity, in mg per unit or % w/w against the label
  • Identity, reported as match or no match against the reference standard
  • With full monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit
Microbiology (injectables)
Endotoxin$210
Sterility or bioburden$150
Container closure integrity (CCI)$50
Screening
Fentanyl screen$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days.

Salts, forms and compendial references

  • USP monographs exist for Lidocaine and Lidocaine Hydrochloride. Full monograph testing is quoted.
  • Tell us the salt or form the label states, so quantity is reported on the same basis.
  • One page covers Lidocaine and its salts and forms.

Questions about Lidocaine testing

Lidocaine base or hydrochloride: does it change the result?

Yes. Lidocaine base is about 87% of anhydrous lidocaine hydrochloride's weight and about 81% of the monohydrate's, so tell us which form the label states.

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity against a reference standard. Full testing to the USP monographs for Lidocaine and Lidocaine Hydrochloride adds the monograph's own tests and is quoted.

Order

Start an order online, or send the compound name and the tests you need for a quote.