Notoginseng (Panax notoginseng)

Notoginseng: botanical (saponin-rich root and rhizome).

Notoginseng testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of a Notoginseng marker compound

Marker compound: 2D structure drawn from the PubChem record (CID 441934).

Compound data

Botanical source

Panax notoginseng Root and Rhizome

Marker compounds

notoginsenoside R1, ginsenoside Rg1, ginsenoside Rb1, ginsenosides Re and Rd

Basis

total or named markers, as your specification states

Type

Botanical (saponin-rich root and rhizome)

Structure and names

Marker compounds: notoginsenoside R1 (CAS 80418-24-2), ginsenoside Rg1 (CAS 22427-39-0), ginsenoside Rb1 (CAS 41753-43-9), ginsenosides Re and Rd

How Vanguard tests Notoginseng

Method for the $250 identity, purity and quantity test: HPLC-UV marker-compound assay (notoginsenoside R1 and ginsenosides Rg1, Re, Rb1 and Rd), LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP Herbal Medicines Compendium monograph covers identity by HPTLC fingerprint and botanical microscopy, and content of notoginsenoside R1 and ginsenosides Rg1, Re, Rb1 and Rd by HPLC. Full testing to the USP Herbal Medicines Compendium monograph for Panax notoginseng Root and Rhizome is available and quoted.

What's reported

  • Marker compounds, as % w/w on the basis your specification states
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Panax notoginseng Root and Rhizome
  • Panax notoginseng Root and Rhizome Dry Extract
  • Panax notoginseng Root and Rhizome Powder
  • Panax notoginseng Root and Rhizome Powdered Extract
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Notoginseng testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV measurement of notoginsenoside R1 and ginsenosides Rg1, Re, Rb1 and Rd, with LC-MS identity. Full testing to the USP Herbal Medicines Compendium monograph for Panax notoginseng Root and Rhizome is available and quoted.

How is notoginseng told apart from Asian or American ginseng?

All three contain ginsenosides, but notoginseng also contains notoginsenoside R1 and has a different ginsenoside pattern. Comparing the saponin profile against reference standards helps flag substitution with other Panax species.

Why are ginsenosides measured at a low UV wavelength?

Ginsenosides absorb UV only weakly, so they are detected near 203 nm, where solvent and matrix background matter more. LC-MS helps confirm peak identity in complex extracts.

What form do notoginseng samples usually arrive in?

Usually dried root pieces, fine powder, powdered extract or capsules. Extracts are often labeled for total saponins, so the label is compared with the sum of the individual marker saponins.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/441934

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.