Paclitaxel: taxane (microtubule stabilizer).
Paclitaxel testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Paclitaxel: 2D structure drawn from the PubChem record (CID 36314).
33069-62-4
C47H51NO14
853.92 g/mol
Taxane (microtubule stabilizer)
Identity: Paclitaxel
IUPAC name: [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC, residue on ignition, optical rotation, water content, microbial enumeration and specified microorganisms, and bacterial endotoxins. Full testing to the USP Paclitaxel monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and quantity and LC-MS for identity. Full testing to the USP Paclitaxel monograph is available and quoted.
Yes. Docetaxel and cephalomannine are close structural relatives with different HPLC retention times and different masses by LC-MS. Cephalomannine is a common related compound in natural-source paclitaxel.
Yes. Paclitaxel can convert to 7-epipaclitaxel in solution, particularly at neutral to basic pH. The epimer has the same mass, so it is separated and measured by HPLC rather than LC-MS alone.
Yes. Paclitaxel from plant extraction, plant cell culture or semisynthesis can carry different related taxanes, so the HPLC impurity profile can look different between suppliers.
https://pubchem.ncbi.nlm.nih.gov/compound/36314
Identity facts from the USP monograph header for this compound.
Start an order online, or send the compound name and the tests you need for a quote.
