Penicillamine: chelating agent (thiol amino acid).
Penicillamine testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Penicillamine: 2D structure drawn from the PubChem record (CID 5852).
52-67-5
C5H11NO2S
149.21 g/mol
Chelating agent (thiol amino acid)
Identity: Penicillamine
IUPAC name: (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid
Method for the $250 identity, purity and quantity test: Chromatographic assay, with detection selected for the compound, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and color reactions, specific rotation, assay by HPLC, a penicillamine disulfide limit by HPLC, a mercury limit, pH, loss on drying, and residue on ignition. Full testing to the USP Penicillamine monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by a chromatographic assay, with detection selected for the compound. Full testing to the USP Penicillamine monograph is available and quoted.
No. The two enantiomers have the same mass and retention time on a standard column. The USP monograph uses optical rotation for this, which is part of full monograph testing.
Penicillamine oxidizes in air and solution to its disulfide dimer. The disulfide separates by HPLC and has a different mass.
Yes. It has no aromatic ring, so the lab uses a detection method suited to the compound.
https://pubchem.ncbi.nlm.nih.gov/compound/5852
Identity facts from the USP monograph header for this compound.
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