Rivaroxaban: anticoagulant (factor Xa inhibitor).
Rivaroxaban testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Rivaroxaban: 2D structure drawn from the PubChem record (CID 9875401).
366789-02-8
C19H18ClN3O5S
435.88 g/mol
Anticoagulant (factor Xa inhibitor)
Identity: Rivaroxaban
IUPAC name: 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities and enantiomeric purity by HPLC, residue on ignition, and water content. Full testing to the USP Rivaroxaban monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and quantity and LC-MS for identity. Full testing to the USP Rivaroxaban monograph is available and quoted.
Rivaroxaban is the S-enantiomer, and the R-enantiomer is a possible impurity. They have the same mass, so a chiral method is needed to measure it, which is quoted separately.
Rivaroxaban has very low water solubility, so it is dissolved in organic solvent before HPLC. Incomplete dissolution can make a sample read low.
https://pubchem.ncbi.nlm.nih.gov/compound/9875401
Identity facts from the USP monograph header for this compound.
Start an order online, or send the compound name and the tests you need for a quote.
