Schisandra (Schisandra chinensis)

Schisandra: botanical (lignan-rich fruit).

Schisandra testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of a Schisandra marker compound

Marker compound: 2D structure drawn from the PubChem record (CID 3001664).

Compound data

Botanical source

Schisandra chinensis Fruit

Marker compounds

schisandrin, schisandrol B (gomisin A, CAS 58546-54-6), deoxyschizandrin, γ-schisandrin

Basis

total or named markers, as your specification states

Type

Botanical (lignan-rich fruit)

Structure and names

Marker compounds: schisandrin (CAS 7432-28-2), schisandrol B (gomisin A, CAS 58546-54-6), deoxyschizandrin (CAS 61281-38-7), γ-schisandrin (CAS 61281-37-6)

How Vanguard tests Schisandra

Method for the $250 identity, purity and quantity test: HPLC-UV marker-compound assay (schisandrin, schisandrol B, deoxyschizandrin and γ-schisandrin), LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP Herbal Medicines Compendium monograph covers identity by HPTLC fingerprint and content of schisandrin, schisandrol B, deoxyschizandrin and γ-schisandrin by HPLC. Full testing to the USP Herbal Medicines Compendium monograph for Schisandra chinensis Fruit is available and quoted.

What's reported

  • Marker compounds, as % w/w on the basis your specification states
  • Quantity, against the label claim
  • Identity, reported as match or no match against the reference standard
  • With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • Schisandra chinensis Fruit
  • Schisandra chinensis Fruit Dry Extract
  • Schisandra chinensis Fruit Powder
  • Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Schisandra testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV measurement of schisandrin, schisandrol B, deoxyschizandrin and γ-schisandrin, with LC-MS identity. Full testing to the USP Herbal Medicines Compendium monograph for Schisandra chinensis Fruit is available and quoted.

Why do schisandra lignans have so many names?

The lignans in schisandra have overlapping common and chemical names; for example, schisandrol B is also called gomisin A, and γ-schisandrin is also called schisandrin B. Results are reported by the monograph names with synonyms noted.

Can southern schisandra be substituted?

Schisandra sphenanthera is a related fruit with a different lignan profile that is lower in schisandrin. Comparing the lignan pattern against reference standards helps flag this substitution.

What form do schisandra samples usually arrive in?

Usually whole dried berries, powder, extract powder or tinctures. Lignans sit mostly in the seed, so whole fruit is ground fully before extraction.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/3001664

Identity facts from the USP monograph header for this compound.

Order

Start an order online, or send the compound name and the tests you need for a quote.