Sodium phenylbutyrate

Sodium phenylbutyrate: aromatic fatty acid sodium salt.

Sodium phenylbutyrate testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

Sodium phenylbutyrate: 2D structure drawn from the PubChem record (CID 5258).

Compound data

CAS number

1716-12-7

Formula

C₁₀H₁₁NaO₂

Molecular weight

186.18 g/mol

Type

Aromatic fatty acid sodium salt

Structure and names

Identity: Sodium phenylbutyrate

IUPAC name: sodium 4-phenylbutanoate

How Vanguard tests Sodium phenylbutyrate

Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP monograph covers identity by infrared spectroscopy and a sodium test, assay by titration, a related compound limit by GC, organic impurities by HPLC, water content and pH. Full testing to the USP Sodium Phenylbutyrate monograph is available and quoted.

What's reported

Purity, as percent of total peak area
Quantity, against the label claim
Identity, reported as match or no match against the reference standard
With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

Purity and quantity

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

Raw powder purity

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on test	Price
Identity and impurities
FTIR identity	$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)	$125
Chiral purity (where a chiral method exists; new methods quoted)	$250
Water, solvents and salt form
Water content by Karl Fischer	$60
Residual solvents	$150
Counterions: chloride, acetate and TFA	$70
Assay
Assay, % w/w (with raw powder purity; $250 together)	+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead	$150
Conformity: purity and quantity on more units from the same lot	$100 per extra unit
Microbiology (injectables)
Endotoxin	$210
Sterility or bioburden	$150
Container closure integrity (CCI)	$50
Screening
Fentanyl screen	$50

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

Sodium Phenylbutyrate (CAS 1716-12-7)
Sodium Phenylbutyrate Oral Powder
Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Sodium phenylbutyrate testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC with UV detection for purity and assay, and LC-MS for identity. Full testing to the USP Sodium Phenylbutyrate monograph is available and quoted.

Is the result reported as phenylbutyrate or sodium phenylbutyrate?

The USP article is the sodium salt, so quantity is reported as sodium phenylbutyrate by default. It can also be reported as phenylbutyric acid if your label uses that basis.