Temozolomide: alkylating agent (imidazotetrazine).
Temozolomide testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Temozolomide: 2D structure drawn from the PubChem record (CID 5394).
85622-93-1
C6H6N6O2
194.15 g/mol
Alkylating agent (imidazotetrazine)
Identity: Temozolomide
IUPAC name: 3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
Method for the $250 identity, purity and quantity test: HPLC-UV purity and assay, LC-MS identity, against a reference standard, with results in 3 to 5 business days.
The USP monograph covers identity by infrared spectroscopy and HPLC retention time, assay by HPLC, organic impurities by HPLC, residue on ignition, and water content. Full testing to the USP Temozolomide monograph is available and quoted.
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
| Microbiology (injectables) | |
| Endotoxin | $210 |
| Sterility or bioburden | $150 |
| Container closure integrity (CCI) | $50 |
| Screening | |
| Fentanyl screen | $50 |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
No. The $250 test covers identity, purity and quantity by HPLC-UV for purity and quantity and LC-MS for identity. Full testing to the USP Temozolomide monograph is available and quoted.
Temozolomide is stable in acid but breaks down quickly at neutral and basic pH to MTIC and then to an aminoimidazole carboxamide product. Samples are prepared in acidic diluent and analyzed promptly.
Usually as a white to light tan powder or as capsules. Capsule contents are extracted and the result is reported per capsule or as percent of label claim.
https://pubchem.ncbi.nlm.nih.gov/compound/5394
Identity facts from the USP monograph header for this compound.
Start an order online, or send the compound name and the tests you need for a quote.
