NAC (N-acetylcysteine)

NAC: acetylated amino acid.

NAC testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

2D structure of NAC

NAC: 2D structure drawn from the PubChem record (CID 12035).

Compound data

CAS number

616-91-1

Formula

C5H9NO3S

Molecular weight

163.20 g/mol (monoisotopic 163.03)

Type

acetylated amino acid

Structure and names

IUPAC name: (2R)-2-acetamido-3-sulfanylpropanoic acid

Other names: acetylcysteine

How Vanguard tests NAC

Identity, purity and quantity are measured by a chromatographic assay, with detection selected for the compound, against a reference standard, $250 per sample with results in 3 to 5 business days. Finished products use the same approach, with sample preparation matched to the product.

Full testing to the USP Acetylcysteine monograph is available and quoted: identification by infrared absorption and assay by HPLC.

What's reported

  • Purity, as percent of total peak area
  • Quantity, in mg per serving or % w/w against the label
  • Identity, reported as match or no match against the reference standard

Tests and prices

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on testPrice
Identity and impurities
FTIR identity$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)$125
Chiral purity (where a chiral method exists; new methods quoted)$250
Water, solvents and salt form
Water content by Karl Fischer$60
Residual solvents$150
Counterions: chloride, acetate and TFA$70
Assay
Assay, % w/w (with raw powder purity; $250 together)+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead$150
Conformity: purity and quantity on more units from the same lot$100 per extra unit

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

  • A USP monograph exists for Acetylcysteine. Monograph testing is quoted.
  • Tell us the salt or form the label states, so quantity is reported on the same basis.
  • One page covers NAC and its salts and forms.

Questions about NAC testing

Can you detect the NAC dimer?

Yes. NAC oxidizes to N,N'-diacetylcystine, which separates by HPLC and lowers the purity result.

Can you test it in a finished product?

Yes. Capsules, powders, gummies and liquids are measured with sample preparation matched to the product, and reported in mg per serving or % w/w against the label.

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity against a reference standard. Full testing to the USP Acetylcysteine monograph adds the monograph's own tests and is quoted.

Other USP titles on this page

USP monographs also exist for these acetylcysteine titles. The $250 identity, purity and quantity test applies to each; testing to the monograph for any of them is available and quoted. Tell us the title your specification names.

  • Acetylcysteine

Order

Send the product name, the form of the ingredient and the label claim for a quote, or submit a sample with the sample form.