Niacin: vitamin B3 (nicotinic acid).
Niacin testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.
Niacin: 2D structure drawn from the PubChem record (CID 938).
59-67-6
C6H5NO2
123.11 g/mol (monoisotopic 123.03)
vitamin B3 (nicotinic acid)
IUPAC name: pyridine-3-carboxylic acid
Other names: nicotinic acid, vitamin B3
Identity, purity and quantity are measured by reversed-phase HPLC with UV detection against a reference standard, $250 per sample with results in 3 to 5 business days. Finished products use the same approach, with sample preparation matched to the product.
Full testing to the USP Niacin monograph is available and quoted: identification by infrared absorption (USP <197M>), UV absorption (USP <197U>) and HPLC retention time against the USP reference standard, assay by HPLC with UV detection and impurities by HPLC.
$250
Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.
| Add-on test | Price |
|---|---|
| Identity and impurities | |
| FTIR identity | $90 |
| CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur) | $125 |
| Chiral purity (where a chiral method exists; new methods quoted) | $250 |
| Water, solvents and salt form | |
| Water content by Karl Fischer | $60 |
| Residual solvents | $150 |
| Counterions: chloride, acetate and TFA | $70 |
| Assay | |
| Assay, % w/w (with raw powder purity; $250 together) | +$50 |
| Metals and conformity | |
| Heavy metals: arsenic, cadmium, chromium, mercury and lead | $150 |
| Conformity: purity and quantity on more units from the same lot | $100 per extra unit |
10% off for 10 or more samples.
Need something else? Other tests are available on request.
Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.
Yes. Nicotinic acid and nicotinamide separate by HPLC and differ by about 1 Da, so a substituted form shows up in the identity result.
No. The $250 test covers identity, purity and quantity against a reference standard. Full testing to the USP Niacin monograph adds the monograph's own tests and is quoted.
USP monographs also exist for these vitamin B3 titles. The $250 identity, purity and quantity test applies to each; testing to the monograph for any of them is available and quoted. Tell us the title your specification names.
Niacinamide (nicotinamide) and niacin (nicotinic acid) separate by HPLC, so the form in a product is identified as well as measured.
Send the product name, the form of the ingredient and the label claim for a quote, or submit a sample with the sample form.
