Bael (Aegle marmelos)

Bael: botanical (fruit).

Bael testing at Vanguard Laboratory: identity, purity and quantity $250 per sample, with results in 3 to 5 business days.

Structure

Marker compound: 2D structure drawn from the PubChem record (CID 10212).

Compound data

Botanical source

Aegle marmelos Fruit

Marker compounds

marmelosin (imperatorin, CAS 482-44-0), aegeline (limit test for absence)

Basis

total or named markers, as your specification states

Type

Botanical (fruit)

Structure and names

Marker compounds: marmelosin (imperatorin, CAS 482-44-0), aegeline (limit test for absence)

How Vanguard tests Bael

Method for the $250 identity, purity and quantity test: HPLC-UV marker-compound assay (marmelosin), LC-MS identity, against a reference standard, with results in 3 to 5 business days.

The USP Herbal Medicines Compendium monograph covers identity by HPTLC fingerprint, content of marmelosin by HPLC, and a test for absence of aegeline. Full testing to the USP Herbal Medicines Compendium monograph for Aegle marmelos Fruit is available and quoted.

What's reported

Marker compounds, as % w/w on the basis your specification states
Quantity, against the label claim
Identity, reported as match or no match against the reference standard
With monograph testing (quoted): the monograph’s tests against its limits

Tests and prices

Purity and quantity

$250

Chromatographic purity and mg per unit by the method matched to the compound, identity against a reference standard. 1 unit.

Raw powder purity

$200

Chromatographic purity on bulk powder. 50 mg.

Add-on tests

Add-on test	Price
Identity and impurities
FTIR identity	$90
CHNS elemental analysis (carbon, hydrogen, nitrogen, sulfur)	$125
Chiral purity (where a chiral method exists; new methods quoted)	$250
Water, solvents and salt form
Water content by Karl Fischer	$60
Residual solvents	$150
Counterions: chloride, acetate and TFA	$70
Assay
Assay, % w/w (with raw powder purity; $250 together)	+$50
Metals and conformity
Heavy metals: arsenic, cadmium, chromium, mercury and lead	$150
Conformity: purity and quantity on more units from the same lot	$100 per extra unit

10% off for 10 or more samples.

Need something else? Other tests are available on request.

Sample amount and turnaround

Purity and quantity is $250 per sample (1 unit) and raw powder purity is $200 for 50 mg, with results in 3 to 5 business days. Send the material sealed and labeled, with the label claim and the form it contains.

Salts, forms and compendial references

Aegle marmelos Fruit
Aegle marmelos Fruit Dry Extract
Aegle marmelos Fruit Powder
Aegle marmelos Ripe Fruit
Aegle marmelos Ripe Fruit Dry Extract
Aegle marmelos Ripe Fruit Powder
Tell us the salt or form the label states, so quantity is reported on the same basis.

Questions about Bael testing

Is the $250 test the same as USP monograph testing?

No. The $250 test covers identity, purity and quantity by HPLC-UV measurement of marmelosin, with LC-MS identity. Full testing to the USP Herbal Medicines Compendium monograph for Aegle marmelos Fruit is available and quoted.

Why does the monograph require no aegeline?

Aegeline is an alkaloid found mainly in bael leaves, not the fruit. Its absence helps show that leaf material or added aegeline is not present.

Is ripe fruit different from unripe fruit?

USP has separate monographs for bael fruit and bael ripe fruit. Both are standardized to marmelosin, and the label should say which is in the product.

Sources

https://pubchem.ncbi.nlm.nih.gov/compound/10212

Identity facts from the USP monograph header for this compound.

Order

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